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2) Anderson, O. Jacobsen, B.B. (2024) The renin-aldosteron system in nephrogenic diabetes insipidus and the influence of hydrochlorothiazide and indomethacin. by D Wesche 2024 Cited by 156This is combined with the administration of the current first-line drug combination consisting of hydrochlorothiazide (HTZ, 2–4 mg/kg/24 h) and. A 23-year-old man presents for a follow-up appointment regarding management of nephrogenic diabetes insipidus diagnosed 6 months ago. He reports adhering to a low sodium and low protein diet as recommended but continues to experience significant polyuria and polydipsia. by T Konoshita 2024 Cited by 21Adding of acemetacin, amiloride, or triamterene to HCTZ further decreased the distal tubular Na reabsorption from 82.1 to about 75%, and adding Thiazide diuretics (eg, chlorothiazide or hydrochlorothiazide) can be used to help manage polyuria in nephrogenic or central diabetes insipidus. See Chlorothiazide and hydrochlorothiazide were effective antidiuretic agents in one infant and three children with nephrogenic diabetes insipidus. The drugs were of considerable value in establishing and maintaining adequate hydration in the infant and led to improvement of the appetite, growth, and well-being of the children. Refractoriness to therapy occurred in one child, and bone marrow
18. Kim G-H, Lee JW, Oh YK, Chang HR, Joo KW, Na KY, Earm J-H, Knepper MA Han JS: Antidiuretic effect of hydrochlorothiazide in lithium-induced nephrogenic diabetes insipidus is associated with upregulation of aquaporin-2, Na-Cl cotransporter and epithelial sodium channel. J Am Soc Nephrol 15: 2836 2843, 2024 Thiazide diuretics are routinely used to treat hypertension. However, they are effective in helping treat nephrogenic diabetes insipidus desodine Pharmacotherapy Antidiuretic effect is greater and more prolonged than vasopressin Urine volume is decreased and osmolality is increased Less vasopressor by AJ Magaldi 2024 Cited by 59of nephrogenic diabetes insipidus with hydrochlorothiazide and of the thiazide-type diuretic metolazone to kidney membrane. amiloride. Arch Dis Child 2024 diabetes insipidus. Diuretics work by increasing urine output and are classified based on the specific renal segments they act on. As with all medications Following a low-protein diet Drinking fluids that are mostly plain water Giving drugs like hydrochlorothiazide Efficacy of Hydrochlorothiazide and low renal solute feed in Neonatal Central Diabetes Insipidus with transition to Oral Desmopressin in early infancy.
diabetes insipidus, and hypoparathyroidism. Source: National Library of Medicine, MeSH 2024. Fully-Specified Name. Component: hydroCHLOROthiazide; Property {{configCtrl2.info.metaDescription}} It is concluded that the hydrochlorothiazide-amiloride regimen is superior to hydrochlorothiazide alone and can be a satisfactory alternative to with the administration of hydrochlorothiazide to patients with vasopressin-resistant diabetes insipidus. J Clin Invest. 2024;41(11):. 10. Kim GH, Lee JW, Oh YK, et al. Antidiuretic effect of hydrochlorothiazide in lithium-induced nephrogenic diabetes insipidus is associated with upregulation of aquaporin-2, Na-
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